Balsamic vinegar helps regulate blood sugar when eaten as part of a meal. Examination of the scientific effects of vinegar found that balsamic vinegar has an antiglycemic impact when consumed, which means that a person's blood sugar will spike less drastically after a meal. It has been shown that balsamic vinegar could help create a blood sugar plateau for a period of up to 5 hours following a meal.

Acetic acid is the active compound in balsamic vinegar and contains strains of probiotics that aid in digestion.  The probiotics contained in acetic acid can help promote good gut health and digestion while supporting overall immune function.

Balsamic vinegar is derived from grapes. Several studies have found that grapes may help prevent cardiac disease by preventing platelets from building up in blood vessels.  Balsamic vinegar also contains polyphenols. Polyphenolic compounds from plants have demonstrated significant benefits to the cardiovascular system. While these compounds are likely to have multiple mechanisms of action for cardiovascular health, one mechanism may be to promote the natural ability of the endothelial lining of blood vessels to relax.  Polyphenols also seem to promote beneficial antioxidant effects in blood vessels by enhancing plasma antioxidant levels, decreasing free radicals and their byproducts, and reducing damage due to oxidative stress.

​The probiotics in balsamic vinegar can also help make a person feel full for longer.  Some studies indicate that people may consume fewer calories throughout the day when they add vinegar to their morning meal.